https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 The Accuracy of the Patient Health Questionnaire-9 Algorithm for Screening to Detect Major Depression: An Individual Participant Data Meta-Analysis https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:39521 Wed 27 Jul 2022 14:01:33 AEST ]]> A case study of an individual participant data meta-analysis of diagnostic accuracy showed that prediction regions represented heterogeneity well https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:50683 Wed 24 Apr 2024 11:33:08 AEST ]]> Comparison of the Accuracy of the 7-Item HADS Depression Subscale and 14-Item Total HADS for Screening for Major Depression: A Systematic Review and Individual Participant Data Meta-Analysis https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:51028 Wed 16 Aug 2023 10:09:34 AEST ]]> A systematic review of the sensitivity and specificity of the toe-brachial index for detecting peripheral artery disease https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:24870 Thu 28 Oct 2021 13:05:13 AEDT ]]> Peripheral blood eosinophils: a surrogate marker for airway eosinophilia in stable COPD https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:29745 9/L vs 0.15×10⁹/L; P<0.0001). Blood eosinophils correlated with both the percentage (ρ=0.535; P<0.0001) and number of sputum eosinophils (ρ=0.473; P<0.0001). Absolute blood eosinophil count was predictive of sputum eosinophilia (area under the curve =0.76, 95% confidence interval [CI] =0.67–0.84; P<0.0001). At a threshold of ≥0.3×10/L (specificity =76%, sensitivity =60%, and positive likelihood ratio =2.5), peripheral blood eosinophil counts enabled identification of the presence or absence of sputum eosinophilia in 71% of the cases. A threshold of ≥0.4×10⁹/L had similar classifying ability but better specificity (91.7%) and higher positive likelihood ratio (3.7). In contrast, ≥0.2×10⁹/L offered a better sensitivity (91.1%) for ruling out sputum eosinophilia. There was a good agreement between two measurements of blood eosinophil count over a median of 28 days (intraclass correlation coefficient =0.8; 95% CI =0.66–0.88; P<0.0001). Conclusion: Peripheral blood eosinophil counts can help identify the presence or absence of sputum eosinophilia in stable COPD patients with a reasonable degree of accuracy.]]> Thu 17 Feb 2022 09:29:13 AEDT ]]> Diagnostic accuracy for self-reported methamphetamine use versus oral fluid test as the reference standard in a methamphetamine-dependent intervention trial population https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:50837 Thu 17 Aug 2023 11:53:14 AEST ]]> How does a short period of exercise effect toe pressures and toe-brachial indices? A cross-sectional exploratory study https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:35451 Thu 13 Jan 2022 10:28:13 AEDT ]]> How sensitive and specific is continuous wave Doppler for detecting peripheral arterial disease in people with and without diabetes? A cross-sectional study https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42754 Thu 01 Sep 2022 14:56:24 AEST ]]> CT perfusion improves diagnostic accuracy and confidence in acute ischaemic stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19328 Sat 24 Mar 2018 07:52:14 AEDT ]]> Quantifying the effect of location matching on accuracy of multiparametric magnetic resonance imaging prior to prostate biopsy—A multicentre study https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:37435 Mon 16 Nov 2020 17:39:51 AEDT ]]> Equivalency of the diagnostic accuracy of the PHQ-8 and PHQ-9: a systematic review and individual participant data meta-analysis https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38673 N = 27). At cutoff 10, the PHQ-8 was less sensitive by 0.02 (−0.06 to 0.00) and more specific by 0.01 (0.00 to 0.01) among those studies (N = 27), with similar results for studies that used other types of interviews (N = 27). For all 54 primary studies combined, across all cutoffs, the PHQ-8 was less sensitive than the PHQ-9 by 0.00 to 0.05 (0.03 at cutoff 10), and specificity was within 0.01 for all cutoffs (0.00 to 0.01). Conclusions: PHQ-8 and PHQ-9 total scores were similar. Sensitivity may be minimally reduced with the PHQ-8, but specificity is similar.]]> Fri 22 Apr 2022 15:27:36 AEST ]]> Toe brachial index measured by automated device compared to duplex ultrasonography for detecting peripheral arterial disease in older people https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:32590 50% arterial obstruction was identified in any lower limb vessel using colour duplex ultrasonography. A receiver operating characteristic curve was analysed and the sensitivity and specificity of commonly used toe brachial index and toe blood pressure values were determined. Results: The optimum toe brachial index threshold value for diagnosing peripheral arterial disease was 0.72 (sensitivity 76.2%, specificity 75%). The area under the curve was 0.829 (95% CI 0.743 to 0.915, p < 0.0001) suggesting fair diagnostic accuracy. A toe blood pressure of 70 mmHg was found to have excellent specificity (97.92%) for detecting PAD but poor sensitivity (42.86%). Conclusions: The accuracy of automated toe blood pressure and TBI measurements was determined to be good when using colour duplex ultrasound as the reference standard for the non-invasive diagnosis of peripheral arterial disease. Results should be interpreted in the context of all clinical signs and symptoms.]]> Fri 01 Apr 2022 09:24:40 AEDT ]]>